Publications by authors named "A I Fokin"

The molecular mechanisms underlying cell migration remain incompletely understood. Here, we show that knock-out cells for NHSL3, the most recently identified member of the Nance-Horan Syndrome family, are more persistent than parental cells in single cell migration, but that, in wound healing, follower cells are impaired in their ability to follow leader cells. The NHSL3 locus encodes several isoforms.

View Article and Find Full Text PDF
Article Synopsis
  • - The study focuses on the magnetic properties of a nanostructured Indium-Silver alloy confined in porous glass, specifically near the eutectic composition, revealing significant interface phenomena in modern physics.
  • - Two superconducting transitions were identified at temperatures 4.05 K and 3.38 K, with unique magnetic behaviors demonstrated through hysteresis loops that indicate both type-I and type-II superconductivity.
  • - The research highlights the emergence of ferromagnetism at the interfaces of indium and silver compounds, even in bulk materials that are not magnetic, pointing to the influence of stray magnetic fields from ferromagnetic regions in the nanostructured alloy.
View Article and Find Full Text PDF

Vinculin is a mechanotransducer that reinforces links between cell adhesions and linear arrays of actin filaments upon myosin-mediated contractility. Both adhesions to the substratum and neighboring cells, however, are initiated within membrane protrusions that originate from Arp2/3-nucleated branched actin networks. Vinculin has been reported to interact with the Arp2/3 complex, but the role of this interaction remains poorly understood.

View Article and Find Full Text PDF

Background: Pelvic fractures (PF) with concomitant injuries are on the rise due to an increase of high-energy trauma. Increase of the elderly population with age related comorbidities further complicates the management. Abdominal organ injuries are kindred with PF due to the proximity to pelvic bones.

View Article and Find Full Text PDF