Publications by authors named "A I ElSherbini"
Atrial and ventricular natriuretic peptides play an important role in the neurohormonal regulation of cardiac function. Plasma levels of these peptides may aid in the diagnosis and prognosis of different cardiac disorders, such as congestive heart failure, ischemic heart disease, and atrial fibrillation. However, the association between elevated pericardial fluid levels of natriuretic peptides and these clinical conditions has not been proven.
View Article and Find Full Text PDFStatement Of Problem: Studies on the significance of intensity on speech production with a tongue prosthesis are lacking, despite this being an important criterion in speech production in patients with total glossectomy.
Purpose: The purpose of this cross-over clinical study was to assess acoustic signal intensity and frequency in patients with total glossectomy rehabilitated with mandibular dentures with 2 different attachment designs for the tongue prosthesis.
Material And Methods: Seven participants initially received a mandibular denture with a tongue prosthesis attached using an acrylic resin plate.
Article Synopsis
- Mitochondrial dysfunction during Alzheimer's disease (AD) is linked to low energy production and increased reactive oxygen species, but the exact mechanisms, particularly related to sphingolipid metabolism, remain unclear.
- In experiments with 5xFAD mice, researchers found that synaptic mitochondria display reduced oxygen consumption and altered protein levels related to energy production as early as 3 months of age.
- The study identified abnormal sphingolipid levels in the mitochondria of 5xFAD mice, with increased long-chain ceramides and sphingosine, indicating that these lipid changes may contribute to mitochondrial dysfunction in early AD development.
Small membranous extracellular vesicles (EV) incorporate proteins and nucleic acids from the parent cell. Proteins exposed on EV surface are dictated by cellular origin and biogenesis pathway. To better understand the EV origin and function, it is important to develop methods that reveal surface protein composition of heterogeneous EV populations in culture supernatants and in biofluids.
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