Etoricoxib pre-medication for post-operative pain after laparoscopic cholecystectomy.

Background: Etoricoxib alleviates and prevents acute pain. The hypothesis of our study was that the pre-operative use of etoricoxib would reduce the post-operative need for additional pain treatment.

Methods: In this double-blind, randomized and active placebo-controlled study, 75 patients were pre-medicated 1.

Lack of analgesic effect of parecoxib following laparoscopic cholecystectomy.

Background: The cyclo-oxygenase-2 inhibitor, parecoxib, can be administered parenterally. The recommended dose for post-operative use is 40 mg twice daily, which may not be the appropriate dose for the treatment of visceral pain. We studied the effect of a single dose of parecoxib of either 40 or 80 mg in laparoscopic cholecystectomy, and its effect on opioid-induced side-effects.

Gordon syndrome and succinylcholine.

We present a case of 6-year-old boy who developed severe hyperkalaemia and ventricular tachycardia after administration of succinylcholine. Ventricular tachycardia was defibrillated and Gordon syndrome, which was diagnosed subsequently, was treated successfully. Paediatric patients with underlying metabolic disorders such as Gordon syndrome are at high risk of developing severe hyperkalaemia after succinylcholine administration.

Children's drawings as a measure of anxiety level: a clinical pilot study.

Background: No simple method exists to distinguish children in need for premedication. The present study was planned to detect preoperative anxiety levels of children by rating their drawings.

Methods: Sixty ASA I children aged 4-7 years undergoing adenoidectomy were divided into AGIT and CALM groups according to agitation level observed during venous cannulation.

Gabapentin for the prevention of postoperative pain after vaginal hysterectomy.

Gabapentin alleviates and/or prevents acute nociceptive and inflammatory pain both in animals and volunteers, especially when given before trauma. Gabapentin might also reduce postoperative pain. To test the hypothesis that gabapentin reduces the postoperative need for additional pain treatment (postoperative opioid sparing effect of gabapentin in humans), we gave 1200 mg of gabapentin or 15 mg of oxazepam (active placebo) 2.