Adherence and forgiveness of two modern ART regimens: lamivudine/dolutegravir and emtricitabine/tenofovir alafenamide/rilpivirine.

Introduction: Few data are available about the forgiveness of two-drug (2DR) or low-barrier three-drug antiretroviral regimens. The aim of this study is to evaluate the real-life forgiveness of lamivudine/dolutegravir (3TC/DTG) and emtricitabine/tenofovir alafenamide/rilpivirine (FTC/TAF/RPV).

Methods: A two center retrospective observational study enrolled all people with HIV (PWH) treated with 3TC/DTG or FTC/TAF/RPV.

MXene-based solvent-responsive actuators with a polymer-intercalated gradient structure.

Actuators based on electrically conductive and hydrophilic two-dimensional (2D) TiCT MXene are of interest for fast and specific responses in demanding environments, such as chemical production. Herein, TiCT -based solvent-responsive bilayer actuators were developed, featuring a gradient polymer-intercalation structure in the active layer. These actuators were assembled using negatively charged pristine TiCT nanosheets as the passive layer and positively charged polymer-tethered TiCT as the active layer.

A highly potential Zn biofortification tool: MTP1 in Triticum aestivum.

TaMTPs belong to metal tolerance proteins (MTPs) family in common wheat and have significant potential to address the "hidden hunger" caused by inadequate dietary intake of a key micronutrient (Zn). In this study, a total of 33 MTP members in Triticum aestivum were identified, among which six TaMTP1-likes were closely related to Arabidopsis thaliana MTP1 and were designated as TaMTP1-A/B/D and TaMTP1.1-A/B/D.

Harnessing Holey MXene/Graphene Oxide Heterostructure to Maximize Ion Channels in Lamellar Film for High-Performance Capacitive Deionization.

2D TiCT MXene-based film electrodes with metallic conductivity and high pseudo-capacitance are of considerable interest in cutting-edge research of capacitive deionization (CDI). Further advancement in practical use is however impeded by their intrinsic limitations, e.g.

Comparison of Synergy Extrapolation and Static Optimization for Estimating Multiple Unmeasured Muscle Activations during Walking.

Background: Calibrated electromyography (EMG)-driven musculoskeletal models can provide great insight into internal quantities (e.g., muscle forces) that are difficult or impossible to measure experimentally.