R-proteins were studied in children with diabetes mellitus and in the risk group. The highest titre of the pattern was found in the children group where diabetes was the first to be detected. Normalization of the R-proteins high titre after insulin therapy was more typical for patients with first detected diabetes as compared with children impaired by the disease within 1-2 years.
View Article and Find Full Text PDFThe cytotoxic activity of lymphocytes of C3HA and C3H (H-2X) mice immunized with the mouse-pathogenic A/PR8/34 (H0N1) and nonpathogenic A/Krasnodar/101/59 (H2N2) strains of influenza virus and with isolated membrane protein was studied. The sensitized lymphocytes were shown to be capable of recognizing and lysing the cells infected with homologous or heterologous virus.
View Article and Find Full Text PDFThe cytotoxic activity of spleen lymphocytes of mice C3H and C3HA lines immunized with whole virions and membrane protein of influenza A/PR8/34 virus strain was studied. The cytotoxic activity of lymphocytes of mice immunized with whole virions was found to be higher for cells of primary mouse kidney cultures inoculated with the homologous virus than for cells of a continuous L929 line. The cytotoxic lymphocytes formed in response to the inoculation with membrane protein have a higher lysing activity for target cells of the continuous L929 line.
View Article and Find Full Text PDF