Bactericidal Activity of Multilayered Hybrid Structures Comprising Titania Nanoparticles and CdSe Quantum Dots under Visible Light.

Titania nanoparticle/CdSe quantum dot hybrid structures are a promising bactericidal coating that exhibits a pronounced effect against light-sensitive bacteria. Here, we report the results of a comprehensive study of the photophysical properties and bactericidal functionality of these hybrid structures on various bacterial strains. We found that our structures provide the efficient generation of superoxide anions under the action of visible light due to electron transfer from QDs to titania nanoparticles with ~60% efficiency.

[Creation of a molecular genetic test system for early diagnosis and evaluation of the effectiveness of treatment of inflammatory periodontal diseases.].

Inflammatory periodontal diseases represent a serious dental and general medical problem due to the high prevalence among the adult population, the presence of clinical forms leading to the destruction of the dentition and tooth loss, insufficient treatment effectiveness and the frequency of relapse, including in connection with the formation of biofilms. A molecular genetic test system has been developed to evaluate the content of periodontopathogenic microorganisms Porphyromonas gingivalis, Treponema denticola, Streptococcus oralis, Streptococcus sanguis and Streptococcus sobrinus in the contents of periodontal pockets. The analytical characteristics of the test system were determined, and testing was carried out on clinical samples of patients with chronic generalized periodontitis of moderate severity.

[Optimization of treatment of wedge-shaped tooth defects with hyperesthesia].

Development of tooth wedge-shaped defect leads to a gradual loss of hard tissue and is characterized by pain. Most often patients complain of pain and aesthetic defect that adversely affects the emotional status and quality of life. Search for adequate means and methods of treatment providing increased resistance of dental hard tissues and reducing hyperesthesia is challenging for dentists.

[Optimization of initial dental caries diagnostics and treatment in patients infected with herpes virus].

The article presents the results of examination and treatment of patients with initial caries (K02.0), infected with herpes virus. Technologies and methods used by most dentists are not sensitive enough to detect caries at early stages, while the remineralizing therapy can be very effective.

Thin-layer chromatographic plates with monolithic layer of silica: production, physical-chemical characteristics, separation capabilities.

The technique for production of thin-layer chromatographic plates with fixed monolithic layer of sorbent was developed on the basis of investigation of factors affecting sorption capacity, sorption kinetics and mechanical stability of monoliths. The optimal reaction mixture for sol-gel synthesis of monoliths consisted of tetraethoxysilane, buffer solution with pH 7.4, N,N-dimethylformamide, ethanol, polyethyleneglycol with molecular weight 1000 and cetylpyridinium chloride in molar ratio 1.