[Assessment of the safety and efficacy of medicinal product PPR-001 based on regulatory polypeptides of the testes].

Objective: Evaluation of the effectiveness and safety of the drug PPR-001 (lyophilizate) in comparison with placebo in men with impaired spermatogenesis.

Materials And Methods: This study was a randomized, double-blind, placebo-controlled, prospective, multicenter, parallel-group research.

Results: It was found that the drug has clinical efficacy and a positive effect on the concentration of spermatozoa in the ejaculate, the percentage of progressively mobile forms and the number of morphologically normal forms of spermatozoa was increased in the group of PPR-001.

Near field focusing by edge diffraction: publisher's note.

This publisher's note corrects an error in the reference section of Opt. Lett.43, 4053 (2018)OPLEDP0146-959210.

Near field focusing by edge diffraction.

Spherical microparticles have the ability for nonresonant focusing of light in the near field zone, forming nanojet (NJ) beams. Arbitrary-shaped microstructures, with wavelength-scale dimensions, may offer similar functionality with lower fabrication complexity. The focusing properties are ruled by the edge diffraction phenomenon.

Impact of 60-GHz millimeter waves on stress and pain-related protein expression in differentiating neuron-like cells.

Millimeter waves (MMW) will be increasingly used for future wireless telecommunications. Previous studies on skin keratinocytes showed that MMW could impact the mRNA expression of Transient Receptor Potential cation channel subfamily Vanilloid, member 2 (TRPV2). Here, we investigated the effect of MMW exposure on this marker, as well as on other membrane receptors such as Transient Receptor Potential cation channel subfamily Vanilloid, member 1 (TRPV1) and purinergic receptor P2X, ligand-gated ion channel, 3 (P2 × 3).

Drastic influence of the half-bowtie resonances on the focusing and collimating capabilities of 2-D extended hemielliptical and hemispherical dielectric lenses.

The interplay between the optical focusing and wavelength-scale resonant features of extended hemielliptical (EHE) and extended hemispherical (EHS) lenses is studied in the two-dimensional (2-D) formulation using highly accurate in-house software based on the Muller boundary integral equations. The influence of the half-bowtie (HBT) resonances on the focusing and collimating capabilities of medium-size EHE and EHS lenses made of silicon is characterized as a function of lens parameters and excitation conditions. As a result, factors determining the parasitic impacts of the HBT resonances on the performance of integrated lens antennas are highlighted.