Publications by authors named "A Husbands"
Functional divergence of transcription factors (TFs) has driven cellular and organismal complexity throughout evolution, but its mechanistic drivers remain poorly understood. Here we test for new mechanisms using CORONA (CNA) and PHABULOSA (PHB), two functionally diverged paralogs in the CLASS III HOMEODOMAIN LEUCINE ZIPPER (HD-ZIPIII) family of TFs. We show that virtually all genes bound by PHB ( ~ 99%) are also bound by CNA, ruling out occupation of distinct sets of genes as a mechanism of functional divergence.
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- Developmental biology isn't as popular or well-funded as it used to be, and other science fields are getting more attention instead.
- A group of scientists from different parts of developmental biology met to discuss problems that are slowing down new discoveries and to suggest ways to fix them.
- They want to "rebrand" the field, get more funding, encourage teamwork between different science areas, improve how science is taught, communicate better, and make sure everyone has equal opportunities and resources.
Leaves are often described in language that evokes a single shape. However, embedded in that descriptor is a multitude of latent shapes arising from evolutionary, developmental, environmental, and other effects. These confounded effects manifest at distinct developmental time points and evolve at different tempos.
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- Flowering plants have adapted over 125 million years to thrive in diverse environments, shaped by interconnected genetic pathways.
- Researchers used topological data analysis (TDA) to effectively analyze complex gene expression data related to plant tissues and stress responses.
- The results show distinct gene expression patterns across different plant types, highlighting core processes essential for plant growth, development, and stress management.
Pick a side: Integrating gene expression and mechanical forces to polarize aerial organs.
Curr Opin Plant Biol
December 2023
How organs acquire their shapes is a central question in developmental biology. In plants, aerial lateral organs such as leaves initiate at the flanks of the growing meristem as dome-shaped primordia. These simple structures then grow out along multiple polarity axes to achieve a dizzying array of final shapes.
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