Publications by authors named "A Hourvitz"
Cryopreserved sperm among patients with Oligoasthenoteratozoospermia.
Eur J Obstet Gynecol Reprod Biol
December 2024
Objectives: This study investigates sperm utilization and disposal patterns in Oligoasthenoteratozoospermia (OAT) patients undergoing long-term sperm storage. OAT is a major contributor to male infertility. Cryopreservation is a common practice as a "fertility insurance" in case of further deterioration until azoospermia.
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- The study focuses on creating a software tool for doctors to predict ovulation timing and evaluate how this affects pregnancy rates in natural cycle frozen embryo transfers (NC-FET).
- Three datasets were analyzed to develop and validate an ovulation prediction model, achieving high accuracy rates (93.85% and 92.89%) in predicting ovulation.
- The results showed that patients who followed the model's predictions had significantly better clinical pregnancy rates compared to those who did not, especially in women under 37 years old.
Article Synopsis
- The study aimed to understand factors affecting the long-term use and disposal of cryopreserved semen straws among cancer patients over nearly three decades.
- Out of 445 participants, 55 used thawed semen for fertility treatments, 65 disposed of their straws, while a majority of 325 did neither, with younger patients showing lower rates of usage and disposal.
- The findings suggest a need for policies on cryopreservation that consider efficiency, cost, and patient demographics, potentially requiring consent from patients before preservation to alleviate unnecessary burdens.
Although many Fertility Centers have adopted day 5 or 6 embryo transfer policy, yet, 30% of embryo transfers in the US are performed on day 3. This is mainly due to concerns related to longer embryo culture effect and higher rates of embryo transfer cancellation on day 5, with no effect on cumulative pregnancy rate. We conducted a retrospective cohort study comparing individual embryo transfer order rank, best embryo for fresh transfer and intention to freeze, of day-3 and day-5 embryos based on their morphology score.
View Article and Find Full Text PDFThe aim of our study was to evaluate if the response to follicular GnRH agonist (GnRHa) trigger be used to predict intracycle ovarian response in GnRH antagonist cycles among women undergoing fertility preservation IVF. We conducted a prospective study of 146 GnRH antagonist oocyte pickup (OPU) cycles to evaluate GnRHa stimulation test (GAST). On day 2 of the cycle, basal E2 were measured, followed by injection of 0.
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