Publications by authors named "A Hosomi"
The phytohormone salicylic acid (SA) regulates plant responses to various types of environmental stress, particularly pathogen infections. We previously revealed that the benzyl alcohol O-benzoyltransferase HSR201 was required for pathogen signal-induced SA synthesis, and its overexpression together with NtCNL, encoding a cinnamate-coenzyme A ligase, was sufficient for the production of significant amounts of SA in tobacco. We herein examined the subcellular localization of HSR201 and found that it fused to a yellow fluorescent protein localized in peroxisomes.
View Article and Find Full Text PDFObjective: This review update aimed to determine the best strategies for assisted bathing or showering for older adults with dementia.
Introduction: Assisted bathing is a high-risk activity, as it can trigger agitated behaviors. Assisted bathing of older adults with dementia can create caregiver challenges and stress.
Human SOD1 is secreted via a conventional secretion pathway in Saccharomyces cerevisiae.
Biochem Biophys Res Commun
July 2023
Article Synopsis
- Soluble proteins typically have an N-terminal signal peptide that guides them to the endoplasmic reticulum (ER) for translocation, but some proteins like SOD1, linked to amyotrophic lateral sclerosis (ALS), do not have this signal.
- Researchers found that SOD1 is still translocated into the ER using the translocon Sec61 and then secreted outside the cell.
- These findings suggest that targeting the secretion process of SOD1 could be a potential therapeutic strategy for treating ALS.