Publications by authors named "A Horie"
Background: Intrauterine peripheral blood mononuclear cell (PBMC) therapy for recurrent implantation failure (RIF) has been reported to improve embryo implantation by acting on the endometrium. However, the exact mode of action of PBMC on the endometrium of patients with RIF remains unclear. In addition, the differences in the therapeutic effects of PBMC therapy with and without human chorionic gonadotropin (hCG) are unknown.
View Article and Find Full Text PDFArticle Synopsis
- A case study highlights a rare infection caused by an endemic mycoplasma after a hysterectomy in a 29-year-old woman with cervical cancer, leading to complications like peritonitis and bowel obstruction.
- The patient's symptoms included fever, ascites, and paralytic ileus, but traditional cultures failed to identify the pathogen.
- Polymerase chain reaction (PCR) testing ultimately detected the mycoplasma, allowing for effective treatment with levofloxacin and leading to the resolution of both the infection and bowel obstruction.
Article Synopsis
- A study conducted in Japan examined the use of comprehensive genomic profiling (CGP) in patients with gynecological cancers, involving nine cancer hospitals and a total of 450 patients.
- The CGP group had fewer cases of cervical cancer and included younger patients compared to the control group, with significant differences in median ages (54 vs. 65 years).
- Although only 12.7% of CGP patients received recommended treatments (mostly not covered by insurance), those who did experienced improved survival rates (median 21 months) compared to others in the CGP group (median 11 months).
Article Synopsis
- Fertility preservation and reproductive treatments in Japan involve significant out-of-pocket expenses for adolescents and young adults, with current healthcare policies lacking in insurance coverage for these services.
- Patients can apply for government subsidies under specific conditions, but the costs and amounts paid vary by facility.
- A study conducted with 186 fertility preservation facilities revealed that about one-third of the expenses are shouldered by patients, highlighting the need for improved pricing and insurance options to ensure ongoing access to care.