Publications by authors named "A Holguin"
Background: There are 39 million people infected by the human immunodeficiency virus (HIV) and 1.3 million new annually infections with more than 150 variants circulating. Early HIV detection is crucial for timely antiretroviral therapy and transmission prevention, but no technique can detect HIV before 10 days of infection.
View Article and Find Full Text PDFTo establish the prevalence of type 2 diabetes, overweight/obesity, and metabolic syndrome in individuals aged >18 years in Bogotá, Colombia and the variables associated with diabetes prevalence. This was a cross‑sectional population survey with a representative, probabilistic sample of Bogotá, Colombia collected between 2022 and 2023. The final sample size included 2,860 households, distributed among 19 localities of Bogotá.
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- Dried blood spots (DBSs) allow researchers to study antibodies for diseases like diphtheria, tetanus, and pertussis without needing blood from veins, making sample collection easier.
- In a study with 64 blood samples, the effectiveness of DBSs in tracking these diseases was assessed, showing high sensitivity and specificity for diphtheria and tetanus, while no protection against pertussis was found.
- The correlation between antibody levels in DBSs and plasma was strong for diphtheria and tetanus even after 4 months of storage at low temperatures, but significantly weaker for pertussis, indicating that DBSs are reliable for some markers but not all.
Proposing the change of name of viruela del mono (monkeypox) in Spanish to viruela M.
Enferm Infecc Microbiol Clin (Engl Ed)
October 2024
Background: In Equatorial Guinea, only 54 % of people living with HIV know their HIV status. There are no confirmatory or molecular diagnostic techniques for early diagnosis or monitoring of infection in the country. Rapid diagnostic tests can induce false-positive diagnoses if used as a confirmatory technique.
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