Publications by authors named "A Hmood Jassim"
Article Synopsis
- * Researchers analyzed data from ESRD patients, collecting blood samples to measure various calcium metabolism biomarkers and identify genetic predictors of vitamin D deficiency using machine learning algorithms.
- * Key findings reveal that certain SNPs are associated with lower levels of specific biomarkers, and machine learning pinpointed rs2221266 and rs1042636 as significant genetic markers for vitamin D deficiency in this population.
Nanobiotechnology, at the intersection of nanotechnology and biology, represents a burgeoning field poised to revolutionize medicine through the use of advanced nanocarriers. These nanocarriers, endowed with distinctive physiobiological attributes, are instrumental in diverse therapeutic domains including drug delivery for microbial infections, cancer treatment, tissue engineering, immunotherapy, and gene therapy. Despite the transformative potential, several challenges hinder their efficacy, such as limited drug capacity, suboptimal targeting, and poor solubility.
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- - The study investigates the role of the P2X7 receptor in causing astrocytes to shift into activated neuroinflammatory states, especially after an increase in intraocular pressure (IOP).
- - Results showed that activating the P2X7 receptor led to a rise in genes indicative of both A1-type and A2-type astrocyte activation, indicating a mixed activation state.
- - The findings suggest that the P2X7 receptor is essential for astrocyte activation in the retina when IOP is elevated, correlating the receptor's activity with both microglial and astrocyte response mechanisms in glaucoma.
Background The purpose of this in vitro investigation was to evaluate the impact of five distinct commercial mouthwashes on the development of that had been adhered to heat-cured acrylic resin sheets. Methods This in vitro investigation was carried out at the MES Medical College's Microbiology Department in Perinthalmanna, Kerala, India. A total of 72 heat-cured acrylic resin sheets, size 10 × 10 × 2 mm, were fabricated.
View Article and Find Full Text PDFAims: To evaluate the association between rs4680 polymorphism in the COMT gene and the vasoconstrictive effects of commonly used vasopressors.
Background: Dopamine is a medication that is given intravenously to critically ill patients to help increase blood pressure. Catechol O-Methyl Transferase (COMT) breaks down dopamine and other catecholamines.