Publications by authors named "A Hille"

Purpose: Neoadjuvant radiochemotherapy (NARCT) is an established standard of care in various tumor entities, promoting high response rates at commonly lower toxicities as compared to adjuvant approaches. This retrospective analysis was designed to investigate NARCT in early-stage high-risk cervical cancer.

Methods: Forty patients with early-stage high-risk cervical cancer (i.

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Background: Malnutrition has a direct impact on both the toxicities of cancer therapy and the overall survival of oncological patients. However, its prevalence amongst vulnerable groups such as older patients (age ≥ 65 years) is often underestimated. Screening tools recognizing patients at risk are well established, yet they do not take into account that cancer therapy may lead to changes in dietary habits or that therapy's side effects may negatively influence nutritional status.

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Background: Telemedicine provides specialized medical expertise in underserved areas where neurological expertise is frequently not available on a daily basis for hospitalized stroke patients. While tele-consultations are well established in acute stroke assessment, the value of telemedicine-based ward-rounds in the subsequent in-patient stroke management is unknown.

Methods: Four telemedicine stroke networks in Germany, implemented in eight out of 16 federal states, participate in this prospective observational multi-center study.

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Article Synopsis
  • Identifying the best treatment for elderly patients with localized non-small cell lung cancer (NSCLC) is difficult, but low-dose cisplatin chemotherapy is a potential option with less toxicity.
  • In a study comparing patients aged 70 and older to younger ones, elderly patients had more health issues and lower stages of cancer, but they experienced fewer severe side effects with low-dose cisplatin compared to cisplatin/vinorelbine.
  • To improve survival outcomes for elderly patients, multimodal treatment strategies, including surgery and systemic therapy, should be considered, and the use of low-dose cisplatin should be tailored to each patient due to its acceptable toxicity profile.
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Background: Significant bleeding of tumor sites is a dreaded complication in oncological diseases and often results in clinical emergencies. Besides basic local and interventional procedures, an urgent radiotherapeutic approach can either achieve a bleeding reduction or a bleeding stop in a vast majority of patients. In spite of being used regularly in clinical practice, data reporting results to this therapy approach is still scarce.

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