Publications by authors named "A Herzum"

Pityriasis rosea (PR) is a self-limited exanthem associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and HHV-7. The disease typically begins with a single erythematous patch on the trunk (herald patch), followed by a secondary eruption of smaller papulosquamous lesions. Rarely, the herald patch may be the only cutaneous manifestation of PR.

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In recent decades, the knowledge on the pathogenesis, immune mechanisms, and molecular signaling pathway underlying inflammatory skin diseases has substantially improved, along with the management of such diseases [...

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Article Synopsis
  • Pityriasis rosea (PR) is a skin condition that usually gets better on its own, often linked to reactivated human herpesviruses, causing mild rashes and itchiness.
  • Traditional treatment focuses on reassuring patients to rest, but severe cases may require medication, prompting a study comparing various treatments.
  • The analysis found that oral steroids and a combo with antihistamines were effective for itch relief, while acyclovir was the most effective for improving rash symptoms, making it the best option for more serious PR cases.
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Jellyfish stings can cause acute inflammatory skin lesions that may hesitate in keloids. Pulsed dye laser (PDL) represents one of the most effective treatments for newly developed keloids. Aim of this study was to evaluate the efficacy of PDL on newly developed keloids specifically induced by jellyfish stings in pediatric patients.

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Article Synopsis
  • Lichen striatus (LS) is a self-resolving skin condition primarily affecting children, characterized by a linear pattern and mainly seen in females, with an average patient age of 3.8 years.
  • A review of 27 articles involving 440 patients suggests that LS may be linked to immune system dysregulation, where cytotoxic T-cells attack skin cells after losing immune tolerance.
  • It is mostly diagnosed clinically based on its unique characteristics, with a typical duration of about 9.5 months, and treatment is rarely needed, highlighting the benign nature of the condition while also pointing out the need for more research in this area.
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