Publications by authors named "A Hernandez-Laguna"
Context: Lenalidomide (LEN) is used for the treatment of myeloma blood cancer disease. It has become one of the most efficient drugs to halt this disease. LEN is a low-soluble drug in aqueous media.
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- - Peptides, particularly cysteine-asparagine-serine (CNS) and serine-asparagine (SN), are being researched for their potential as anti-inflammatory drugs, but their molecular interactions are not fully understood.
- - The study utilized density functional theory (DFT) calculations to confirm the crystal structure of SN, which helped validate findings related to CNS and its spectroscopic properties.
- - The research found that CNS can intercalate into montmorillonite (MNT), leading to significant changes in its conformation, which may enhance its stability and efficacy for therapeutic anti-inflammatory applications.
Tetroxane derivatives are interesting drugs for antileishmaniasis and antimalaric treatments. The gas-phase thermal decomposition of 3,6,-dimethyl-1,2,4,5-tetroxane (DMT) and 3,3,6,6,-tetramethyl-1,2,4,5-tetroxane (acetone diperoxide (ACDP)) was studied at 493-543 K by direct gas chromatography by means of a flow reactor. The reaction is produced in the injector chamber at different temperatures.
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- The use of antibiotics in agriculture has significantly increased, leading to rising levels of these substances in soil, particularly from intensive farming and human consumption.
- This study examines how ciprofloxacin, an antibiotic, interacts with clay minerals in soils from Santa Rosa, Argentina, using both experimental methods and atomistic modeling.
- Findings reveal two types of ciprofloxacin adsorption on clay minerals: a weakly bound form that gets released during desorption and a strongly bound form that persists in the soil.
Layered double hydroxides (LDHs) are important components in terrestrial and extra-terrestrial environments. The presence of iron in these minerals provides them a wide potential application in environmental and materials sciences. In this work, the role of Fe in the crystallographic properties of LDHs M:M 2:1 with Mg:(Fe,Al), Mg:Fe, Zn:(Fe,Al), and Zn:Fe is investigated by means of quantum mechanical calculations based on the density functional theory (DFT).
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