Publications by authors named "A Hauge"
Long-term effect and safety of mesenchymal stromal cell therapy for radiation-induced hyposalivation in head and neck cancer survivors: A randomised, phase-2, trial.
Clin Cancer Res
January 2025
Background: The long-term effect of adipose-derived mesenchymal stromal cells (ASCs) to restore radiation-induced salivary gland hypofunction in previous head and neck cancer patients have not been validated in larger settings.
Methods: The study was the 12-months follow-up of a randomised trial, including patients with hyposalivation. Patients were randomised to receive allogeneic ASCs or placebo in the submandibular glands.
Organizing to address overtreatment in cancer care near the end of life: Evidence from Denmark.
J Health Serv Res Policy
December 2024
Objectives: The purpose of this study is to investigate how organizational factors influence the ethical and economic problems of overtreatment of cancer patients.
Methods: The study applies a sequential mixed-method approach. First, our logistic regression model assesses how patient characteristics and hospital department variables influence the use of late cancer treatment (LCT), primarily chemotherapy, in stage IV non-small cell lung cancer cases using Danish registry data.
Article Synopsis
- Large-volume therapeutic phlebotomy is the main treatment for hemochromatosis and allows researchers to study blood flow changes during low blood volume conditions.
- A 64-year-old male patient with hemochromatosis underwent 1000 mL phlebotomy on nine occasions, during which he was closely monitored for vital signs and tolerance.
- The study found that the patient successfully maintained blood pressure through increased heart rate and vascular resistance, indicating that this phlebotomy method can safely model blood loss scenarios in clinical settings.
In this study we have asked a group of autistic young adults to describe what is important for their quality of life. The 14 participants (aged 21-29 years) were recruited from a 10-year follow-up study of autistic people. During interviews, our participants described the importance of having relationships with family, friends and pets.
View Article and Find Full Text PDFBackground: Adipose-derived mesenchymal stem/stromal cells (ASCs) are proposed as a new xerostomia treatment. The study evaluated the long-term safety and effectiveness of allogeneic ASCs in radiation-induced xerostomia among patients with previous oropharyngeal cancer.
Methods: This study constitutes 3-year follow-up on the original 10 patients who received allogeneic ASCs injections to the submandibular and parotid glands as part of the MESRIX-II trial.