Publications by authors named "A Hassler"
Article Synopsis
- The study focused on exploring the effects of hyperbaric oxygen therapy (HBOT) on critical COVID-19 patients suffering from moderate acute respiratory distress syndrome at a Swedish university hospital.
- Patients were randomly assigned to receive either HBOT plus best practice care or best practice care alone, with a follow-up period of 30 days.
- Results showed that those in the HBOT group had a unique gene expression related to endoplasmic reticulum stress, leading to faster recovery and a significantly shorter hospital stay compared to the control group.
Background: Few treatment options exist for patients with COVID-19-induced acute respiratory distress syndrome (ARDS). Data on the benefits and harms of hyperbaric oxygen treatment (HBOT) for this condition is limited.
Objective: To evaluate benefits and harms of HBOT in patients with COVID-19 induced ARDS.
Within the national opioid epidemic, there has been an increase in the number of infants exposed to opioids in utero. Additionally, opioid agonist medications are the standard of care for women with opioid use disorder during pregnancy. Buprenorphine (BUP), a partial µ -opioid receptor agonist, has been successful in improving gestational and neonatal outcomes.
View Article and Find Full Text PDFRationale: Understanding the interactions between marine mammals and their environment is critical for ecological and conservation purposes. Odontocetes offer a continuous record of their life history from birth as recorded in annual increments of their tooth dentine. Because dentine is not remodeled and contains collagen, nitrogen stable isotope compositions (δ N) reflect nursing and weaning events, life history traits that would otherwise be impossible to retrieve in such elusive marine animals.
View Article and Find Full Text PDFBackground: A few prospective trials and case series have suggested that hyperbaric oxygen therapy (HBOT) may be efficacious for the treatment of severe COVID-19, but safety is a concern for critically ill patients. We present an interim analysis of the safety of HBOT via a randomized controlled trial (COVID-19-HBO).
Methods: A randomized controlled, open-label, clinical trial was conducted in compliance with good clinical practice to explore the safety and efficacy of HBOT for severe COVID-19 in critically ill patients with moderate acute respiratory distress syndrome (ARDS).