Developing high-yielding and resilient maize hybrids is essential to ensure its sustainable production with the ongoing challenges of considerable shifts in global climate. This study aimed to explore genetic diversity among exotic and local maize inbred lines, evaluate their combining ability, understand the genetic mechanisms influencing ear characteristics and grain yield, and identify superior hybrids suited for timely and late sowing conditions. Seven local and exotic maize inbred lines were genotyped using SSR (Simple Sequence Repeat) markers to assess their genetic diversity.
View Article and Find Full Text PDFBackground: Osteomyelitis (OM) associated with diabetic foot ulceration (DFU) is a growing public health challenge worldwide. Since 2012 the number of patients presenting with DFU per year to our centre has doubled.
Objective: This study aims to evaluate outcomes from outpatient antibiotic therapy (OPAT) in the management of OM in DFU patients.
Historically, for more than one and a half centuries, only one so-called "long-legged bat tick" species, i.e., Koch was known to science.
View Article and Find Full Text PDFSeveral microRNAs (miRNAs), including miR-221-5p, Let-7b-5p, miR-21-5p, miR-9-5p, miR-126-3p, and miR-222-3p, were recently found to be enriched in circulating exosomes of patients with non-small cell lung cancers (NSCLCs). These miRNAs distinguished cancer cases from controls with high precision and were predicted to modulate the expression of genes within the oncogenic LINE-1 regulatory network. To test this hypothesis, plasma exosomes from controls, early, and late-stage NSCLC patients were co-cultured with non-tumorigenic lung epithelial cells for 72 h and processed for measurements of gene expression.
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