Publications by authors named "A Hasani"
Breast cancer (BC) is a prevalent and highly lethal cancer in females. Like other cancer types, the intricate cellular and molecular heterogeneity leads to the variation of therapeutic outcomes. The development and progression of blood vessels increase the tumor cell expansion and metastasis to remote sites.
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- The human gut hosts trillions of microbes that play a key role in health, but imbalances (dysbiosis) can lead to chronic conditions like inflammatory bowel disease (IBD).
- IBD, a significant global health concern, includes two major types: ulcerative colitis and Crohn's disease, both characterized by inflammation in the digestive system.
- To address the rising rates and severity of IBD, modifying gut microbiota through dietary supplements like prebiotics, probiotics, paraprobiotics, and postbiotics can be explored as potential treatment options.
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- The study investigated the mutation rate of the envelope (E) gene of SARS-CoV-2 in COVID-19 patients, focusing on its conformational characteristics.
- Out of 120 patients, 10 nucleotide changes were found in the E gene, with 2 missense mutations (L73F and S68F) that alter amino acids, while most changes were silent.
- The mutations were shown to introduce new helix structures in the E protein and potentially enhance its stability and binding to specific proteins, which could affect viral spread and immune cell response in the lungs.
The gut-brain axis plays an important role in mental health. The intestinal epithelial surface is colonized by billions of commensal and transitory bacteria, known as the Gut Microbiota (GM). However, potential pathogens continuously stimulate intestinal immunity when they find the place.
View Article and Find Full Text PDFBackground: Myxomas are the most common primary benign heart tumors, typically found in the left atrium, with only 2-4% occurring in the right ventricle. Clinical presentations vary widely, including congestive heart failure and systemic embolic phenomena. This case report describes a rare right ventricular myxoma causing both inflow and outflow obstruction, presenting as progressive exertional dyspnea.
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