Publications by authors named "A Harxhi"

Introduction: Coronary artery disease (CAD) and peripheral artery disease (PAD) increase the risks of cardiovascular events and death. Digital health technologies are rapidly expanding to improve healthcare quality and access. The Care4Today Connect (C4T CAD-PAD) mobile application is designed to help patients with CAD and/or PAD improve medication adherence, learn about their disease, make lifestyle modifications, and enhance healthcare provider (HCP) connection via an HCP-facing portal.

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Objectives: We aimed to assess the extent of integration of non-communicable disease (NCD) assessment and management in HIV clinics across Europe.

Methods: A structured electronic questionnaire with 41 multiple-choice and rating-scale questions assessing NCD assessment and management was sent to 88 HIV clinics across the WHO European Region during March-May 2023. One response per clinic was collected.

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Article Synopsis
  • There is ongoing uncertainty about the relationship between SARS-CoV-2 and HIV, specifically regarding the risks for individuals infected with both viruses.
  • A study involving 536 HIV-positive patients in central and eastern Europe revealed that low CD4 cell counts and detectable HIV viral loads are linked to increased severity of COVID-19 symptoms.
  • Findings suggest that a lower HIV viral load correlates with less severe COVID-19 outcomes, indicating its potential use as a prognostic tool for clinicians treating co-infected patients.
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Background: Venous congestion (VC) is a hallmark of symptomatic heart failure (HF) requiring hospitalization; however, its role in the pathogenesis of HF progression remains unclear. We investigated whether peripheral VC exacerbates inflammation, oxidative stress and neurohormonal and endothelial cell (EC) activation in patients with HF with reduced ejection fraction (HFrEF).

Methods And Results: Two matched groups of patients with HFrEF and with no peripheral VC vs without recent HF hospitalization were studied.

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