Publications by authors named "A Hartner"
Mathematical models are established tools to assist in outbreak response. They help characterise complex patterns in disease spread, simulate control options to assist public health authorities in decision-making, and longer-term operational and financial planning. In the context of vaccine-preventable diseases (VPDs), vaccines are one of the most-cost effective outbreak response interventions, with the potential to avert significant morbidity and mortality through timely delivery.
View Article and Find Full Text PDFObjectives: We conducted a rapid review to determine the extent that immunisation services in low-income and middle-income countries (LMICs) were disrupted by the COVID-19 pandemic and synthesised the factors that can be used to build resilience in future.
Design: Rapid review reported in accordance with the Preferred reporting for Systematic reviews and Meta-Analyses (PRISMA) guidelines.
Data Sources: PubMed and Web of Science were searched through 6 October 2023.
Article Synopsis
- The global immunization coverage has decreased during the COVID-19 pandemic, leading to under-immunized groups and impacting efforts to control vaccine-preventable diseases.
- This study utilized modeling from 112 low- and middle-income countries to assess the effects of disrupted vaccine coverage on 14 diseases and identify regions needing recovery efforts.
- Results were derived from historical vaccine coverage data and aimed to understand whether lost immunization advantages could be regained through targeted catch-up initiatives.
Background: Malaysia introduced the two dose measles-mumps-rubella (MMR) vaccine in 2004 as part of its measles elimination strategy. However, despite high historical coverage of MCV1 and MCV2, Malaysia continues to report high measles incidence. This study suggests a novel indicator for investigating population immunity against measles in the Malaysian population.
View Article and Find Full Text PDFBackground: Clinical studies suggest that female sex plays a protective role in the development and progression of kidney disease. Recent experimental studies indicate that in male rats early nephron loss under ongoing nephrogenesis is accompanied by severe long-term sequelae. In humans, nephron formation occurs mainly in the third trimester, ceasing with 36 weeks of gestation.
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