Acquired factor XIII deficiency in myeloid neoplasms: case series and review of literature.

Acquired factor XIII (FXIII) deficiency is a rare disorder that could be associated with autoimmune and malignant disorders with a high risk of bleeding. In acute leukemias, acquired FXIII deficiency has been reported and replacement of FXIII helped to control significant bleeding. Here, we report four cases of myeloid neoplasms to have acquired FXIII deficiency with interesting concomitant RUNX1 mutation in the molecular background of two patients.

Megameatus intact prepuce: a systematic review of surgical techniques and long-term outcomes.

Megameatus intact prepuce (MIP) presents with diverse phenotypes that complicate the management of this rare but complex hypospadias variant. Current data on optimal treatment methods and patient outcomes are sparse, unintegrated, and therefore challenging to implement clinically. A comprehensive systematic review of the existing literature on MIP was conducted according to PRISMA guidelines.

Periodontal and Caries Status in Relation to Oral Health Knowledge, Attitudes, and Behavior of Medical and Dental Students in Taxila, Pakistan.

Background The importance of oral health in general well-being is widely acknowledged. It is expected that students belonging to dental and medical fields maintain a strong awareness of oral health and participate in public oral health awareness and initiatives, particularly in low-income nations such as Pakistan. Objectives The objective of the study was to assess the relation of periodontal status and dental caries status of medical and dental students in Taxila, Pakistan, with their oral health knowledge, attitude, and behavior.

Local wound care management for pyoderma gangrenosum.

Pyoderma gangrenosum (PG) is a rare, painful neutrophilic dermatosis characterized by rapidly progressing skin ulcers. Despite the importance of local wound care in managing PG, there is no consensus or evidence-based guidelines. This systematic review aimed to investigate local wound care strategies for PG.