Identification, seasonal prevalence, and preferred attachment sites of ixodid tick species infesting cattle in four municipalities of the province of Tiaret, northwest Algeria.

Ixodid ticks are important disease vectors that significantly impact animal health and cause considerable economic losses, particularly in tropical and subtropical countries. The aim of the present study was to determine the identity, seasonal distribution, and preferred attachment sites of adult ixodid tick species of cattle in four municipalities (Aïn El Hadid, Sidi Bakhti, Mechraa Safa, and Sidi Hosni) of the Province of Tiaret (north-west Algeria) between May 2022 and May 2023. A total of 317 cattle were randomly selected and examined for tick infestation; 108 (34.

Vibration dataset of main journal bearings in internal combustion engines under diverse climatic and varying operating conditions.

The dataset includes vibration signatures from both healthy and faulty main journal bearings of an internal combustion engine, captured with a tri-axial accelerometer mounted on the bearings' housing. The engine was exposed to various climatic and operating conditions, including variations in temperature and humidity, and tested at different engine rotation speeds, following a standard, MIL-STD-810G. The data was collected in a state-of-the-art climatic and vibration chamber to simulate real-world environmental conditions.

Endogenous CD4 T cells that recognize ALK and the NPM1::ALK fusion protein can be expanded from human peripheral blood.

Anaplastic lymphoma kinase (ALK)-fusion proteins resulting from chromosomal rearrangements are promising targets for cancer immunotherapy. While ALK-specific CD8+ T cells and epitopes presented on MHC class I have been identified in patients with ALK-positive malignancies, little is known about ALK-specific CD4+ T cells. We screened peripheral blood of ten ALK-positive anaplastic large cell lymphoma (ALK+ALCL) patients in remission and six healthy donors for CD4+ T-cell responses to the whole ALK-fusion protein, nucleophosmin (NPM1)::ALK.

Lymph Node Yield/Ratio, Neutrophil-Lymphocyte Ratio: Prognostic Factors in cN0 Laryngeal Carcinoma.

Objectives: The aim of this study was to investigate the role of lymph node yield (LNY), lymph node ratio (LNR), and neutrophil to lymphocyte ratio (NLR) as prognostic factors, their impact on survival in patients with advanced laryngeal squamous cell carcinoma (LSCC).

Methods: This multicentric retrospective study included 195 patients with clinical N0 advanced laryngeal carcinoma who underwent total laryngectomy and/or total pharyngolaryngectomy over 5 years. The number of lymph nodes extracted (LNY) and the number of positive nodes were counted.

pH induced structural and conformational changes in nucleocapsid protein leads to intermediate like conformation: a biophysical and computational approach.

Nucleocapsid protein (N) of SARS-CoV-2 is a multivalent protein, which is responsible for viral replication, assembly, packaging and modulates host immune response. In this study, we report conformational measurements of N protein at different pH by observing transition in secondary and tertiary structural contents by biophysical and computational approaches. Spectroscopic measurements revealed that N protein loses its secondary and tertiary structure at extreme acidic pH while maintaining its native conformation at mild acidic and alkaline pH.