Publications by authors named "A Hampton"

Article Synopsis
  • - The study focuses on CNS neuroblastoma (CNS NB-FOXR2), a brain tumor subtype linked to the transcription factor FOXR2, but its origins and mechanisms are not fully understood.
  • - Researchers conducted gene expression analysis and created a human embryonic stem cell model to identify the tumor's cell of origin and investigate how CNS NB-FOXR2 forms.
  • - Findings revealed that the tumors originate from medial ganglionic eminence (MGE) progenitor cells and that FOXR2 activates the MEK/ERK signaling pathway, suggesting a potential target for treatment.
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Article Synopsis
  • * It compares the drought responses of two plant species: sweet corn, which disconnects from soil during severe drought, and peanut, which maintains its connection.
  • * Findings indicate that while hyperspectral reflectance can predict soil water status for peanuts, it fails for sweet corn once disconnection occurs, highlighting the need for species-specific approaches in predicting soil water status.
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Community-based chronic disease prevention programs can have long-term, broad public health benefits. Yet, only 40 to 60% of evidence-based health programs are sustained. Using established frameworks and evidence-based tools to characterize sustainability allows programs to develop structures and processes to leverage resources effectively to sustain effective program activities and systems.

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How are we to understand and research health law under devolution in the UK? Building on work in law and geography, we argue that the figure of the border is key to the production and implementation of devolved health law and the variety of forms that this takes. The utility of border thinking in this context is shown through a review of thematic areas, including infectious disease control, access to health care, and abortion, each instantiating a distinct bordering process. In each, we consider recent developments in policy and legislation, framed with reference to constitutional change, and the politics of devolution in the UK.

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Defective brain glucose utilization is a hallmark of Alzheimer's disease (AD) while Type II diabetes and elevated blood glucose escalate the risk for AD in later life. Isolating contributions of normal aging from coincident metabolic or brain diseases could lead to refined approaches to manage specific health risks and optimize treatments targeted to susceptible older individuals. We evaluated metabolic, neuroendocrine, and neurobiological differences between young adult (6 months) and aged (24 months) male rats.

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