Incidence of antibodies in women after failure of assisted reproduction.

Objectives: The aim of this study is to determine to what degree antisperm allo-antibodies (ASA), anti-ovarian antibodies (AOA), anti-zona pellucida antibodies (AZPA) and seven anti-phospholipid antibodies (APLA) can explain the failure of assisted reproduction technology (ART) in women.

Background: Among the causes of reproductive failure are allo- and autoimmune reactions of the organism against reproductive tissues and cells.

Methods: We examined a sample of 43 selected women aged 27 to 45 after failure of assisted reproduction technology (ART) via intrauterine insemination (IUI), in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).

[Corelation between hyperviscosity of the ejaculate and physical-morphological and biochemical parameters].

Objective: The aim of our study was to investigate the corelation between hyperviscosity and physical-morphological and biochemical parameters of the ejaculate and potential influence of local infections on spermatic plasma viscosity and observed parameters.

Design: Retrospective analysis.

Setting: Associated Tissue Bank of P.

[Immunohistologic determination of extracellular matrix components in granuloma annulare].

Background: The histological diagnosis of granuloma annulare is based on assessment of a palisade-like granuloma and necrobiosis. The authors attempt to make a more accurate diagnosis of the disease based on immunohistological assessment of components of the extracellular matrix.

Methods And Results: In a group of 15 patients with granuloma annulare the authors assessed, using the immunoperoxidase method, collagens type I, III and V and fibronectin.

[Fibronectin, interstitial collagens and type IV collagen in dermatitis herpetiformis].

Background: In the pathogenesis of dermatitis herpetiformis the participation of some proteins of the extracellular matrix has not been elucidated so far. They are found more amply in the papillary derma where they are manifested most markedly as the mentioned type of dermatosis. The objective of the present work was to assess the participation of components of the extracellular matrix in the pathogenesis of diseases and the possibility of their detection to make a more accurate diagnosis.

[Determination of antithrombin III in situ in the skin of patients with allergic arteriolitis].

The authors assessed antithrombin III in patients with allergic arteriolitis. Positive expression of antithrombin was assessed on endothelia, thrombi and infiltrate cells in approximately 2/3 of patients of the examined group (n = 23). The authors assume that expression of antithrombin III reflects inhibited hemocoagulation in the affected vessels as well as inhibition of leucocyte proteases in the above disease.