Publications by authors named "A Hakan Vural"

Clinical Relevance: Endonasal dacryocystorhinostomy (EN-DCR) is one of the preferred interventions for occlusion of the nasolacrimal drainage system. Understanding the bulbar conjunctival changes that occur after EN-DCR surgery will provide better insight into the effect of this procedure on visual quality and patient comfort.

Background: This study aimed to evaluate visual quality and bulbar conjunctival cytologic changes using in vivo confocal microscopy and corneal topography in patients with epiphora resulting from nasolacrimal duct obstruction after EN-DCR.

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Objective: To compare the results of one-step surgery (OSS) and two-step surgery (TSS) in the surgical management of eyelid basal cell carcinomas (BCC).

Method: A total of 43 eyes of 43 patients were included. OSS was applied to 22 of these patients, while TSS was applied to 21 patients.

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Sex is an important covariate in all genetic and epigenetic research due to its role in the incidence, progression and outcome of many phenotypic characteristics and human diseases. Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with a sex bias towards higher incidence in males. Here, we report for the first time a blood-based epigenome-wide association study meta-analysis in 9274 individuals after stringent quality control (5529 males and 3975 females).

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  • A study assessed work-related anxiety levels among healthcare workers in emergency departments (ED) using surveys, including Beck's Anxiety Inventory (BAI) and the Mini-International Neuropsychiatric Interview (MINI).
  • Out of 130 participants, 43.8% scored above the anxiety threshold on the BAI, with higher scores linked to factors like gender, job dissatisfaction, and previous anxiety disorders.
  • The findings indicate teaching coping strategies for trauma and phobias could help reduce anxiety disorders among ED healthcare workers.
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  • The study evaluated how renal tumor biopsy (RTB) impacted the success of trifecta criteria in patients who underwent open partial nephrectomy (OPN) for renal cancer from 2012 to 2023.
  • Out of 167 patients, trifecta achievement rates were similar between the RTB group (53.3%) and the non-RTB group (54.76%), indicating no significant difference in surgical outcomes.
  • However, the RTB group showed a higher incidence of lymphovascular invasion, suggesting that while RTB is safe, it may be associated with some negative pathology outcomes.
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