Publications by authors named "A Haczku"
Article Synopsis
- - The study examines how exposure to wildfire smoke impacts immune responses in individuals receiving the Pfizer COVID-19 vaccine, focusing on the role of Natural Killer (NK) cells.
- - Researchers analyzed blood samples from 52 participants before and after vaccine administration during heavy wildfire smoke events, finding variations in IgG antibody levels associated with air quality.
- - Results indicate that wildfire smoke exposure may disrupt immune function by affecting NK cell activity, leading to reduced vaccine efficacy over time.
Background: Population growth and climate change have led to more frequent and larger wildfires, increasing the exposure of individuals to wildfire smoke. Notably, asthma exacerbations and allergic airway sensitization are prominent outcomes of such exposure.
Summary: Key research questions relate to determining the precise impact on individuals with asthma, including the severity, duration, and long-term consequences of exacerbations.
Background: Wildfires are a global concern due to their wide-ranging environmental, economic, and public health impacts. Climate change contributes to an increase in the frequency and intensity of wildfires making smoke exposure a more significant and recurring health concern for individuals with airway diseases. Some of the most prominent effects of wildfire smoke exposure are asthma exacerbations and allergic airway sensitization.
View Article and Find Full Text PDFRationale: Pulmonary innate immune cells play a central role in the initiation and perpetuation of chronic obstructive pulmonary disease (COPD), however the precise mechanisms that orchestrate the development and severity of COPD are poorly understood.
Objectives: We hypothesized that the recently described family of innate lymphoid cells (ILCs) play an important role in COPD.
Methods: Subjects with COPD and healthy controls were clinically evaluated, and their sputum samples were assessed by flow cytometry.