Publications by authors named "A Hachiya"

Background: Perimembranous ventricular septal defect (VSD) can be classified as having trabecular, inlet, or outlet extension. The surgical approach used in patch closure depends on the which valve of the tricuspid valve to suture around and the avoidance of the specialized conducting system. This retrospective study evaluated the usefulness of the "En face view" method for classifying perimembranous VSD.

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  • The study aimed to assess the long-term effectiveness and safety of endoscopic myoneurectomy (EMN) of the thyroarytenoid muscle in treating adductor spasmodic dysphonia (AdSD), focusing on vocal outcomes and complications.
  • Out of 48 patients treated, 79.2% experienced success, with significant improvements in vocal function reflected in a drop in the Voice Handicap Index score from 97 to 26 post-treatment.
  • While some patients faced adverse effects like granulomas and glottic insufficiency, the procedure demonstrated high success rates and minimal complications, highlighting its benefits for vocal improvement.
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Background: Integrase strand transfer inhibitors (INSTIs) are recommended as first-line ART for people living with HIV (PLWH) in most guidelines. The INSTI-resistance-associated mutation E157Q, a highly prevalent (2%-5%) polymorphism of the HIV-1 (human immunodeficiency virus type 1) integrase gene, has limited data on optimal first-line ART regimens. We assessed the virological outcomes of various first-line ART regimens in PLWH with E157Q in real-world settings.

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  • - Late HIV diagnosis in Japan is a significant issue, particularly among young men who have sex with men (MSM) in urban areas, and the study aimed to understand various factors contributing to this problem, including demographics and clinical aspects.
  • - The research analyzed anonymized data from nearly 10,000 newly diagnosed HIV cases from 2003 to 2019, revealing that 71.2% of participants experienced late diagnosis, with a median CD4 count of 221 cells/μl at diagnosis.
  • - Key factors linked to late HIV diagnosis included older age, heterosexual transmission, living outside of Tokyo, co-infection with hepatitis C, and not being part of a genetic cluster, while a specific HIV subtype (CRF
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Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been widely used. They inhibit proximal tubular glucose reabsorption, resulting in glycosuria. Herein, we report the case of a 65-year-old woman who presented with hypernatremia during the perioperative period of a subarachnoid hemorrhage.

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