Publications by authors named "A HALAWANI"
Background: The Rh blood group system (ISBT004) is encoded by two homologous genes, RHD and RHCE. Polymorphism in these two genes gives rise to 56 antigens, which are highly immunogenic and clinically significant. This study extended previous work on the establishment of RHD allele specific reference sequences using next generation sequencing (NGS) with the Ion Personal Genome Machine (Ion PGM) to sequence the complete RHCE gene.
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- In southwestern Saudi Arabia, inherited blood disorders and malaria are common, necessitating careful blood transfusion compatibility due to potential alloimmunization when blood group antigens are mismatched.
- This study examined the allele/genotype frequencies of the Wright blood groups in 150 blood donors from Jazan Province, finding that only one specific allele and genotype were present among the participants.
- The research concludes that the Jazan population may have a higher susceptibility to certain invasions, and suggests that including Wright alleles in transfusion screening may not be necessary.*
Background: The incorporation of Artificial Intelligence (AI) into healthcare sector has fundamentally transformed patient care paradigms, particularly through the creation of patient education materials (PEMs) tailored to individual needs. This Study aims to assess the precision and readability AI-generated information on kidney cancer using ChatGPT 4.0, Gemini AI, and Perplexity AI.
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- The study investigates the clinical features, causes, and outcomes of meningitis and encephalitis in adults in Saudi Arabia, aiming to fill a knowledge gap about these serious CNS infections.* -
- Conducted as a retrospective single-center study from March 2016 to May 2022, it revealed that most infections were caused by unidentified pathogens and that a significant portion of patients had received antibiotics before lumbar puncture.* -
- The findings emphasized the need for timely treatment according to guidelines and suggested the creation of national biobanks to improve the understanding of meningitis and encephalitis in Saudi Arabia.*
Purpose: Jazan Province in Saudi Arabia is notable for its high prevalence of inherited hemoglobinopathies, including sickle cell disease and thalassemia, necessitating frequent blood transfusions for affected individuals. To mitigate risks such as RBC alloimmunization and hemolytic transfusion reactions, ensuring blood compatibility is crucial. The Kell (KEL) blood group system, pivotal alongside the ABO and RH systems, encompasses multiple antigens implicated in these complications.
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