Publications by authors named "A H W Bruns"

During recent decades, changes in lifestyle have led to widespread nutritional obesity and its related complications. Remodelling adipose tissue as a therapeutic goal for obesity and its complications has attracted much attention and continues to be actively explored. The endothelium lines all blood vessels and is close to all cells, including adipocytes.

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The propulsive fins of ray-finned fish are used for large scale locomotion and fine maneuvering, yet also provide sensory feedback regarding hydrodynamic loading and the surrounding environment. This information is gathered via nerve cells in the webbing between their fin rays. A similar bioinspired system that can gather force feedback from fin motion could enable valuable insight into robotic underwater locomotion improving swimming efficiency and orientation.

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Article Synopsis
  • Translational magnetic resonance imaging of rodent brains is crucial for drug development, but automated image segmentation is challenging due to lower image quality compared to human MRI.
  • The study explored the effectiveness of deep learning models for segmenting rat brain images into multiple regions, using a robust method that accommodates variability in animal strain and size.
  • Among the models tested, the Attention U-Net performed best, providing accurate segmentation while minimizing the reliance on costly manual labels, and included features for uncertainty estimation and explainability for quality assurance.
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Past research shows that emotion affects beauty judgments of images and music. Because it is widely supposed that our faculty of empathy facilitates aesthetic experience, we wondered whether individual levels of empathy modulate the effect of emotion on beauty. 164 participants rated the perceived beauty, happiness, and sadness of 12 art images, 12 nature photographs, and 24 songs.

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Primary secretory carcinoma (SC) of the thyroid gland is a rare neoplasm, characterized by the presence of oncogenic ETV6::NTRK3 fusions, which are amenable to tropomyosin receptor kinase (TRK) inhibitor therapy. Despite its morphologic, immunophenotypic, and genetic similarities to SC of the salivary and mammary glands, diagnostic pitfalls may arise in differentiating from papillary thyroid carcinoma due to overlapping features such as papillary growth, nuclear irregularity, and variable expression of PAX8. Tumor misclassification may lead to delayed consideration of molecular testing and targeted therapy.

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