Publications by authors named "A H Uchida"

Transition metal dichalcogenides (TMDs) exhibit unique properties and potential applications when reduced to one-dimensional (1D) nanoribbons (NRs), owing to quantum confinement and high edge densities. However, effective growth methods for self-aligned TMD NRs are still lacking. We demonstrate a versatile approach for lattice-guided growth of dense, aligned MoS NR arrays via chemical vapor deposition (CVD) on anisotropic sapphire substrates, without tailored surface steps.

View Article and Find Full Text PDF

Aberrant immune responses to viral pathogens contribute to pathogenesis, but our understanding of pathological immune responses caused by viruses within the human virome, especially at a population scale, remains limited. We analyzed whole-genome sequencing datasets of 6,321 Japanese individuals, including patients with autoimmune diseases (psoriasis vulgaris, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), pulmonary alveolar proteinosis (PAP) or multiple sclerosis) and coronavirus disease 2019 (COVID-19), or healthy controls. We systematically quantified two constituents of the blood DNA virome, endogenous HHV-6 (eHHV-6) and anellovirus.

View Article and Find Full Text PDF

Social isolation affects physical functioning owing to psychological stress. We constructed a rat model to clarify the unexplored effects of social isolation and to determine whether environmental changes as an intervention against social isolation can reduce the stress-inducing effects of social isolation on physiological factors. Eight-week-old male rats were divided into three groups: group-housed, isolated, and intervention.

View Article and Find Full Text PDF
Article Synopsis
  • Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus that may be linked to cancer, prompting a study to explore this association.
  • A cohort study in Sweden analyzed 1,580 EoE patients and matched them with 7,533 reference individuals, tracking cancer development over a median of 7 years.
  • While no overall cancer risk was found in EoE patients, there was a significant increase in the risk of esophageal cancer and Barrett's esophagus, though these cases were very rare, warranting caution in interpreting the results.
View Article and Find Full Text PDF

This study analyzes entropy of broadband chaos excited in a semiconductor laser subject to intensity-modulated optical injection for random number generation with guaranteed unpredictability. It is identified that the flattening of spectral profile around the laser relaxation resonance blurs the periodicity it brings, and thus leads to a high entropy value and a high random number generation rate. The effect of measurement device noise on entropy suggests that both the power of chaos needs to be kept at a level to achieve an adequate signal-to-noise ratio, 24 dB or more, and the entropy contribution of the measurement device noise is excluded in order to assert entropy that can be extracted solely from the intrinsic property of chaos.

View Article and Find Full Text PDF