Publications by authors named "A H To"
Recent advancements in spatial transcriptomics and spatial proteomics enabled the high-throughput profiling of single or multi-cell types and cell states with spatial information. They transformed our understanding of the higher-order architectures and paired cell-cell interactions within a tumor microenvironment (TME). Within less than a decade, this rapidly emerging field has discovered much crucial fundamental knowledge and significantly improved clinical diagnosis in the field of immuno-oncology.
View Article and Find Full Text PDFThis study examined various factors, including social support as a mediating one, influencing subjective unmet needs (SUN) in Vietnamese older people during the COVID-19 pandemic. Using logistic regression models with a national survey on older persons, we identified determinants of SUN, and then further explored how social support moderated the association between experiencing SUN and chronic diseases. We found that about 25% of Vietnamese older persons experienced SUN during the pandemic, in which more advanced age, living alone, lack of healthcare insurance and having chronic diseases were risk factors, while higher education, better wealth, and stronger social support played as protective factors.
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- A crack-free Stellite-6 alloy was successfully fabricated using a laser powder bed fusion method with a heating module for the first time, involving a heated build plate at 400 °C.
- Two printing combinations (sample A: 300 W/750 mm/s; sample B: 275 W/1000 mm/s) were used, resulting in FCC-Co dendrites and W-rich MC particles, with some gas pores noted that necessitated a hot isostatic pressing (HIP) process at 1250 °C.
- After HIP, sample A showed partial recrystallization and coarsened MC, while sample B experienced complete recrystallization and increased grain growth, with the microhardness post-HIP being slightly higher than traditional
Synthesis and Application of D- and C-Labelled tert-Butyl Hoechst Dye.
J Labelled Comp Radiopharm
November 2024
Herein, the successful syntheses of D- and C-N-methyl and D-tert-butyl Hoechst dyes are presented. This includes the preparation of the labelled D- and C-N-methyl piperazines and D-tert-butylated hydroxytoluene precursors. The tert-butyl Hoechst dye is known to bind a specific RNA aptamer.
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- * Researchers developed two types of serological assays in Liberia to assess COVID-19 exposure in four counties, analyzing 189 samples collected in summer 2021.
- * The assays revealed significant exposure to SARS-CoV-2 and other viruses, while also identifying inhibitory antibodies in the samples, which could help improve serological testing capabilities in underrepresented regions.