This study presents the development of biocompatible and biodegradable nanocomposites utilizing renewable cellulose nanocrystals (CNCs) in polycaprolactone (PCL)-based polyurethane acrylates (PUA) through in situ polymerization. First, CNCs were derived from cotton linter via acid hydrolysis; then functionalized with 3-methacryloxypropyltrimethoxysilane to produce silane-modified CNCs (S-CNCs). CNCs offered uniform dispersion in PUA up to 2 wt% loading, resulting in significant property enhancements, including ∼60 % increase in tensile strength and ∼25 % increase in Young's modulus.
View Article and Find Full Text PDFBackground: Glioblastoma multiforme (GBM) is the most malignant brain tumor, with a poor prognosis and life expectancy of 14-16 months after diagnosis. The standard treatment for GBM consists of surgery, radiotherapy, and chemotherapy with temozolomide. Most patients become resistant to treatment after some time, and the tumor recurs.
View Article and Find Full Text PDFPurpose: To evaluate the effect of early posttrabeculectomy bleb leakage on trabeculectomy surgery outcomes and success rate.
Methods: The present prospective cohort study was conducted on 203 eyes of 203 patients who underwent trabeculectomy at Torfeh and Imam Hossein Medical Centers, Tehran, Iran, between 2016 and 2021. Patients were divided into two groups: those with early bleb leakage (within the 1 month of surgery) and those without bleb leakage.