Recurrent PAK2 rearrangements in poroma with folliculo-sebaceous differentiation.

Aims: Poroma is a benign adnexal neoplasm with differentiation towards the upper portion of the sweat gland apparatus. In 2019, Sekine et al. demonstrated recurrent YAP1::MAML2 and YAP1::NUTM1 fusion in poroma and porocarcinoma.

Outcome of Patients with Advanced Heart Failure Who Receive Device-Based Therapy for Primary Prevention of Sudden Cardiac Death: Insights from the Israeli ICD Registry.

Background: Randomized clinical trials have shown conflicting data on the benefit of implantable cardioverter defibrillator (ICD) for primary prevention of sudden cardiac death in patients with more advanced heart failure (HF) symptoms. Using the Israeli ICD Registry data, we sought to examine the effect of HF functional class on the outcome of patients who receive device therapy in a real-world setting.

Methods: The association between HF functional class (categorized as baseline New York Heart Association [NYHA] functional class I and II in [61%] vs class III and IV in [39%]) and clinical outcomes was assessed among 913 patients who received an ICD (n = 514) or a cardiac resynchronization therapy with a defibrillator (CRT-D; n = 399) device and were prospectively followed in the Israeli ICD Registry between July 2011 and June 2013.

[Role of virus infection as etiological factors of miscarriage].

Epstein-Barr virus (human herpes virus fourth type HSV-4 NNV-4) is by far one of the most common human viruses, including during pregnancy. Aim of this work was to study the impact of Epstein-Barr virus infection in pregnancy as the fetus fading in the later stages. A significant degree of persistence of infection we set to 64% of women.

Disparities in disability among non-Hispanic black elders: results from the National Interview Survey 2001-2003.

A drastically increasing elderly population and disparity among disability poses a concern for the U.S. health care industry.