Publications by authors named "A H Maurer"

Objectives: Gastroparesis is a complication following lung transplantation. This study aimed to assess the prevalence of gastroparesis in patients with lung transplants undergoing solid phase gastric emptying scintigraphy (GES). Specifically, we investigated which type of lung transplant is more susceptible to gastroparesis and whether timing of GES post-transplantation impacts diagnosis of severe gastroparesis.

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We report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus.

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Article Synopsis
  • This study aimed to explore how different stomach shapes observed in gastric emptying scintigraphy (GES) relate to gastric emptying speeds, body weight, and GI symptoms.
  • Researchers reviewed 397 GES studies, identifying five stomach shapes: crescentic, J-shaped, reversed-L, cylindrical, and bag-like, with crescentic being the most common.
  • Findings revealed that crescentic stomachs had the highest body mass index (BMI), while bag-like stomachs showed the slowest gastric emptying and more severe regurgitation and heartburn symptoms.
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Article Synopsis
  • The text discusses the challenge of identifying somatic variants through single-cell RNA sequencing (scRNA-seq) due to issues like low transcript reads and protocol biases, which can miss critical genetic information.
  • It introduces SIGURD (SIngle cell level Genotyping Using scRNA Data), an R-based tool designed to analyze scRNA-seq data by combining somatic and mitochondrial variants for more effective clonal analysis.
  • SIGURD enables researchers to assess clonal relationships, gene expression changes, and how these variants relate to specific cell populations, as demonstrated through its application on cells from patients with myeloproliferative neoplasms.
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Pangenomes are collections of annotated genome sequences of multiple individuals of a species. The structural variants uncovered by these datasets are a major asset to genetic analysis in crop plants. Here we report a pangenome of barley comprising long-read sequence assemblies of 76 wild and domesticated genomes and short-read sequence data of 1,315 genotypes.

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