Publications by authors named "A H Gaba"

Purpose Of Review: Nutition has long been of importance in the care of Huntington's disease (HD). The purpose of this review is to summarize recent research relevant to HD nutrition, and to describe some emerging theoretical approaches to research in this area.

Recent Findings: Clinical studies have identified swallowing problems and fear of choking as major impediments to maintaining nutritional status with HD.

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Several APOBEC3 enzymes restrict HIV-1 by deaminating cytosine to form uracil in single-stranded proviral (-)DNA. However, HIV-1 Vif counteracts their activity by inducing their proteasomal degradation. This counteraction by Vif is incomplete, as evidenced by footprints of APOBEC3-mediated mutations within integrated proviral genomes of people living with HIV-1.

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Article Synopsis
  • The study investigates how reallocating time among physical activity, sedentary behavior, and sleep affects obesity indicators like BMI and waist circumference across various age groups.
  • Researchers analyzed data from 9,818 participants using isotemporal substitution models to understand the implications of these behavior changes.
  • Results indicated that even small shifts of 10-30 minutes can significantly impact obesity, with reallocating moderate-to-vigorous physical activity (MVPA) to lighter activities or sedentary behavior having particularly detrimental effects.
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Objectives: The objective of this study was to identify typologies of activity-related behaviours during adolescence and to explore transitions between the identified typologies. Additionally, we aimed to identify demographic indicators associated with the transitions and typology membership.

Design: Prospective cohort study.

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Article Synopsis
  • The study examined sleep patterns among Slovak adolescents to see how these relate to body fat and fitness levels.
  • Using data from over 8,900 young people, researchers identified three sleep groups: optimal sleepers, those with occasional sleep issues, and poor sleepers.
  • Findings revealed that poor sleepers had more body fat and lower fitness; however, only the link to fitness remained significant after further analysis, suggesting these insights could inform health interventions for teens.
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