Publications by authors named "A H Ashour"
Introduction: First metatarsophalangeal (MTP) joint fusion is a widely accepted surgical intervention for treating severe arthritis, deformities, and instability of the first MTP joint. This paper provides a review of a single surgeon's experience with continuous compression implants (CCI), which offer a notable advantage by providing uniform compression across a larger surface area of the fusion site compared to plate and screw constructs. This design potentially reduces soft tissue irritation and, consequently, the need for subsequent implant removal.
View Article and Find Full Text PDFA simple and highly effective Schiff-base fluorescent chemosensor (S1) was synthesized and characterized by HNMR and fluorescence spectroscopy. The synthesized chemosensor was applied for the selective and sensitive detection of Hg ions. The chemosensor exhibited a strong 'turn-on' fluorescence response in a CHOH/HO (1:9, v/v) solution due to complex formation (S1-Hg) which block photo induce electron transfer (PET).
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- The increasing issue of multidrug resistance (MDR) in pathogenic bacteria like Staphylococcus aureus has prompted the search for new treatment methods, including FDA-drug repurposing.
- Ambroxol was tested against clinical MDR S. aureus isolates and showed effective antibacterial activity, with concentrations needed to inhibit growth between 0.75 to 1.5 mg/mL, and also disrupted biofilm formation in about 42% of the isolates.
- In vivo studies demonstrated ambroxol's ability to enhance skin tissue healing in S. aureus infected burn injuries by reducing bacterial presence and inflammation, with further investigations suggesting its action may involve binding to several targets in the bacterium.
The correlation between epigenetic alterations and the pathophysiology of human infertility is progressively being elucidated with the discovery of an increasing number of target genes that exhibit altered expression patterns linked to reproductive abnormalities. Several genes and molecules are emerging as important for the future management of human infertility. In men, microRNAs (miRNAs) like miR-34c, miR-34b, and miR-122 regulate apoptosis, sperm production, and germ cell survival, while other factors, such as miR-449 and sirtuin 1 (SIRT1), influence testicular health, oxidative stress, and mitochondrial function.
View Article and Find Full Text PDFObjective: To compare the accuracy of arthroscopy with MRI in diagnosing ramp lesions associated with anterior cruciate ligament (ACL) injuries.
Design: Prospective observational study. Material and We included 100 patients with complete ACL tear.