Publications by authors named "A H Al-Salem"

This work reports the performances of the magnetic chitosan@graphene oxide composite (MCh@GO) for the sorption of Nd(III) from aqueous medium. The prepared composite was synthesized by a coprecipitation method and then examined by FT-IR, XRD, SEM, and TGA. XRD analysis proved physical interactions between magnetic chitosan and graphene oxide through (inter- and intramolecular H-bonding and peptide bonding).

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Article Synopsis
  • Dental healthcare personnel are at risk of exposure to infectious diseases when administering local anesthesia, and despite safety measures, needle stick injuries still occur.
  • The study involved 67 dental professionals using dental tweezers and various forceps to recap needles, comparing this method's safety and ease to the traditional one-hand scoop technique.
  • Results showed no significant difference in ease of use between techniques, with over 40% satisfaction for the one-hand scoop, indicating the need for improved safety practices in dental settings.
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We provide promising computational (in silico) data on phytochemicals (compounds -) from Arabian Peninsula medicinal plants as strong binders, targeting 3-chymotrypsin-like protease (3CL) and papain-like proteases (PL) of SARS-CoV-2. Compounds - followed the Lipinski rules of five (RO5) and ADMET analysis, exhibiting drug-like characters. Non-covalent (reversible) docking of compounds - demonstrated their binding with the catalytic dyad (CYS145 and HIS41) of 3CL and catalytic triad (CYS111, HIS272, and ASP286) of PL.

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Background: Targeting non-pulmonary vein triggers (NPVTs) after pulmonary vein isolation may reduce atrial fibrillation (AF) recurrence. Isoproterenol infusion and cardioversion of spontaneous or induced AF can provoke NPVTs but typically require vasopressor support and increased procedural time.

Objective: The purpose of this study was to identify risk factors for the presence of NPVTs and create a risk score to identify higher-risk subgroups.

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COVID-19, a disease caused by SARS-CoV-2, has caused a huge loss of human life, and the number of deaths is still continuing. Despite the lack of repurposed drugs and vaccines, the search for potential small molecules to inhibit SARS-CoV-2 is in demand. Hence, we relied on the drug-like characters of ten phytochemicals (compounds -) that were previously isolated and purified by our research team from Saudi medicinal plants.

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