Use of azole compounds for the treatment of experimental aspergillosis in turkeys.

A model for aspergillosis by injecting fungal spores into the lung is described. The model permits evaluation of anti-mycotic agents and their effect on the development of lesions in the infected lung, the spreading to the second lung and other organs. The therapeutic effect of the azole compounds enilconazole, ketoconazole, itraconazole and levamisole was determined.

Vaccination of young turkeys against fowl cholera.

Turkey poults vaccinated at one day of age with commercial inactivated Pasteurella multocida (PM) bacterin responded with low titres of antibody (ab) as measured by ELISA, but had an acceptable degree of resistance when challenged with the X-73 strain of PM until 13 weeks of age. Turkeys vaccinated at 3 and/or 6 weeks of age responded with higher ab titres and were resistant to virulent challenge with PM. Turkey poults vaccinated at 3 and/or 6 weeks of age with a commercial live PM vaccine had a poor immune response and low resistance to virulent challenge.

Pox in ostriches.

Clinical signs suggesting pox were observed in a flock of ostrich chicks (Struthio camelus), 10 to 60 days old. The disease was confirmed by isolation of the agent from affected ostriches and reproduction of typical pox lesions in turkeys. Further infection of young ostriches was prevented by vaccination with fowl pox vaccine.

Clinical and pathological changes caused by the interaction of lasalocid and chloramphenicol in broiler chickens.

Uncommon and abnormal gait, characterised by toe walking and progressive leg weakness, was observed in a large broiler flock in Israel. Identical clinical signs were reproduced when young chicks received feed supplemented with lasalocid (Abatec-Roche), and chloramphenicol at normal recommended levels, for 12 days or more. The clinical and pathological findings suggest a neuromuscular toxic effect of lasalocid-chloramphenicol interaction in broiler chicks.

Infectious synovitis in turkeys: Isolation of tenosynovitis virus-like agent.

A virus was isolated from the diseased hock joints of turkeys suffering from infectious synovitis. Results in the agar gel precipitation test indicate that the virus is identical with tenosynovitis virus of chickens. Mycoplasma synoviae was also isolated from the hock of an afflicted bird during the same outbreak.