Publications by authors named "A Gulino"
Article Synopsis
- Hydrogen peroxide is important in biology and medicine as it affects cellular processes and helps the body fight infections and oxidative stress.
- This study focuses on using tris(3-hydroxypyridin-4-one) (THP) to create a new electrochemical sensor for detecting hydrogen peroxide, which has shown effective results with a low detection limit.
- The sensor demonstrates high sensitivity, stability, and potential for use in biological samples, representing a significant advancement in electrochemical sensor technology for biomedical applications.
The practical and easy detection of dopamine levels in human fluids, such as urine and saliva, is of great interest due to the correlation of dopamine concentration with several diseases. In this work, the one-step synthesis of water-soluble carbon nanoparticles (CNPs), starting from artichoke extract, containing catechol groups, for the fluorescence sensing of dopamine is reported. Size, morphology, chemical composition and electronic structure of CNPs were elucidated by DLS, AFM, XPS, FT-IR, EDX and TEM analyses.
View Article and Find Full Text PDFHigh-entropy alloys (HEAs) are a class of metal alloys consisting of four or more molar equal or near-equal elements. HEA nanomaterials have garnered significant interest due to their wide range of applications, such as electrocatalysis, welding, and brazing. Their unique multi-principle high-entropy effect allows for the tailoring of the alloy composition to facilitate specific electrochemical reactions.
View Article and Find Full Text PDFArticle Synopsis
- Zero-dimensional boron nitride quantum dots (BNQDs) have promising optical, chemical, and biochemical properties, especially when integrated with carbon, specifically phenolic groups for biomedical applications.
- The first direct synthesis of water-dispersible BNQDs containing phenolic and carboxylic groups is accomplished through a single-step solvent-assisted reaction, and various characterization methods confirm their stability and unique luminescent properties.
- The carbon-BNQDs show biocompatibility with cancer cells, offering protection against oxidative stress, and analyzing mRNA-seq expression provides insight into their protective molecular effects.
Acute myeloid leukemia (AML) progression is influenced by immune suppression induced by leukemia cells. ZEB1, a critical transcription factor in epithelial-to-mesenchymal transition, demonstrates immune regulatory functions in AML. Silencing ZEB1 in leukemic cells reduces engraftment and extramedullary disease in immune-competent mice, activating CD8 T lymphocytes and limiting Th17 cell expansion.
View Article and Find Full Text PDF