Publications by authors named "A Guillien"
Background: Viral infections in childhood, especially to rhinovirus (RV) and respiratory syncytial virus (RSV), are associated with asthma inception and exacerbation. However, little is known about the role of RV- and RSV-specific antibodies in childhood versus adult asthma.
Objective: We sought to investigate associations between RV- and RSV-specific IgG levels and asthma phenotypes in children and adults.
Introduction: Exposure to respiratory viruses is a significant cause of morbidity and affects virus-specific antibody levels. Little is known about determinants associated with immune response to these viruses. We aimed to investigate the determinants of respiratory syncytial virus (RSV)- and rhinovirus (RV)- specific IgG responses in both children and adults.
View Article and Find Full Text PDFIntroduction: Previous studies identified some environmental and lifestyle factors independently associated with children respiratory health, but few focused on exposure mixture effects. This study aimed at identifying, in pregnancy and in childhood, combined urban and lifestyle environment profiles associated with respiratory health in children.
Methods: This study is based on the European Human Early-Life Exposome (HELIX) project, combining six birth cohorts.
Article Synopsis
- Forced vital capacity (FVC) and lung transfer of carbon monoxide (TLCO) are both important tests for measuring how bad a lung disease called idiopathic pulmonary fibrosis (IPF) is, but TLCO is better at showing the disease's severity.
- * In a study of 430 IPF patients, many with "normal" FVC actually had "abnormal" TLCO, meaning FVC alone might not tell the whole story about lung health.
- * The research found that most patients with a decline in TLCO also had a decline in FVC, but the opposite was not true, suggesting TLCO should be given more attention in monitoring IPF.
Purpose: The main objective of this study was to identify risk factors for post-percutaneous transthoracic lung biopsy (PTLB) pneumothorax and to establish and validate a predictive score for pneumothorax occurrence to identify patients eligible for outpatient care.
Material And Methods: Patients who underwent PTLB between November 1, 2012 and March 1, 2017 were retrospectively evaluated for clinical and radiologic factors potentially related to pneumothorax occurrence. Multivariate logistic regression was used to identify risk factors, and the model coefficient for each factor was used to compute a score.