Publications by authors named "A Grzesiak"

Article Synopsis
  • The Hammersmith Score (HS) is a validated prognostic tool that helps predict response and survival rates in early-phase cancer trial participants based on routine biochemical measures.
  • A study analyzed 212 patient referrals, finding that HS significantly predicted overall survival and outperformed the Royal Marsden Score (RMS) in its predictive ability.
  • HS offers a simple and cost-effective method to improve patient selection and referral for early-phase cancer trials, especially in the context of modern cancer immunotherapy.
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High-throughput (HTP) research is becoming more widely utilized due to its advantages in rapid screening of large parameter space. When HTP is used for reaction screening, often only the end products are analyzed by off-line techniques, leaving behind valuable process information. Information-rich spectroscopy tools have remained under-utilized in HTP workflows.

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The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and replacing them with polyunsaturated fatty acids (PUFAs) n-3 (omega-3) and n-6 (omega-6) to decrease the risk of metabolic disturbances. Consequently, excessive n-6 PUFAs content and high n-6/n-3 ratio are found in Western-type diet. The importance of a dietary n-6/n-3 ratio to prevent chronic diseases is linked with anti-inflammatory functions of linolenic acid (ALA, 18:3n-3) and longer-chain n-3 PUFAs.

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The NHS faces challenges in recruiting and retaining GPs. The NHS Long Term Plan aims to increase NHS staffing levels as one of its objectives. The Induction and Refresher (I&R) Scheme supports this aim by providing a safe induction or return to UK practice for GPs who are new to UK general practice or who have been away from it for 2 years or more.

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A novel interdisciplinary team approach within a primary care setting may be a promising model for delivering effective comprehensive treatment options for patients with chronic pain.

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