Publications by authors named "A Grondona"

The restrictive measures implemented to stem the spread of COVID-19 abruptly changed the lives of many cats and their owners. This study explored whether the lockdown in Italy affected the cat-owner relationship, as well as cat behaviour and welfare. A survey that included questions on owner and cat's demographics, living environment, cat behaviour and a modified version of the Cat/Dog Relationship Scale (C/DORS) was distributed online during the lockdown and was completed by 548 cat owners, mainly women (81.

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The quantitative determination of average roughness parameters, from the determination of height variations of the surface points, is frequently used to estimate the adhesion between an adhesive and the surface of a substrate. However, to determine the interaction between an adhesive and a surface of a heterogeneous material, such as a red ceramic, it is essential to define other roughness parameters. This work proposes a method for determining the roughness of red ceramic blocks from a three-dimensional evaluation, with the objective of estimating the contact area that the ceramic substrate can provide for a cementitious matrix.

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Introduction: Few data are available regarding the trend of IgA anti-transglutaminase antibodies (TGA-IgA) in children with celiac disease (CD) on a gluten-free diet (GFD). Our aim is to examine the normalization time of CD serology in a large pediatric population, and its predictors.

Material And Methods: We retrospectively evaluated the normalization time of TGA-IgA and its predictive factors (age, sex, ethnicity, symptoms, associated diabetes/thyroiditis, Marsh stage, TGA-IgA and endomysial antibody levels at diagnosis, diet adherence), in 1024 children diagnosed from 2000 to 2019 in three pediatric Italian centers, on a GFD.

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Background: Autoantibodies against-phospholipase A2 receptor (PLA2R) are specific markers of idiopathic membranous nephropathy (iMN). Enzyme-linked immunosorbent assay (ELISA) is becoming the preferred method in many laboratories for the determination of anti-PLA2R antibodies, because it provides quantitative results, and is not prone to subjective interpretation, as is the case with indirect immunofluorescence assay.

Methods: The purpose of our study was to determine the diagnostic performance of serum PLA2R antibodies detected by commercially available ELISA in a large Italian multicenter cohort of patients with biopsy-proven iMN and in patients with other renal diseases, with special focus on evaluating the optimal cut-off value to discriminate positive and negative results.

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Article Synopsis
  • COVID-19 is linked to interstitial pneumonia, and this study investigates the presence of autoimmune markers in patients suffering from the disease.
  • Out of 33 COVID-19 patients studied, 45% tested positive for at least one type of autoantibody, with higher rates among those who died during hospitalization.
  • Those with autoantibodies showed more severe symptoms and a worse prognosis compared to those without, highlighting the need for further research on the relationship between autoimmunity and COVID-19 outcomes.
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