Laryngeal precursor lesions: Interrater and intrarater reliability of histopathological assessment.

Objective: The World Health Organization classification (WHOC) 2017 of low-grade versus high-grade laryngeal dysplasia recently replaced the previous WHOC 2005 of mild, moderate, and severe dysplasia and carcinoma in situ. Our objectives were to compare the interrater agreement of the WHOC 2017 with that of the WHOC 2005 and to test the intra-rater agreement of the WHOC 2005.

Methods: Two expert head and neck pathologists rated 211 tissue samples that were initially diagnosed with laryngeal precursor lesions.

Cross-cultural Adaption and Validation of the Danish Voice Handicap Index.

Objectives: We aimed to assess psychometric properties, including internal consistency, reliability, and clinical validity of the Danish version of the Voice Handicap Index (VHI).

Study Design: A cross-sectional survey study was carried out.

Methods: For validation, the existing nonvalidated Danish version of the VHI was used.

Can the Ni classification of vessels predict neoplasia? A systematic review and meta-analysis.

Objectives: The Ni classification of vascular change from 2011 is well documented for evaluating pharyngeal and laryngeal lesions, primarily focusing on cancer. In the planning of surgery it may be more relevant to differentiate neoplasia from non-neoplasia. We aimed to evaluate the ability of the Ni classification to predict laryngeal or hypopharyngeal neoplasia and to investigate if a changed cutoff value would support the recent European Laryngological Society (ELS) proposal of perpendicular vascular changes as indicative of neoplasia.

Can videostroboscopy predict early glottic cancer? A systematic review and meta-analysis.

Objective: Correct assessment of patients with a glottic lesion is crucial for ensuring proper treatment in cases of cancer or premalignancy and for avoiding unnecessary surgery. For years, videostroboscopy (VS) has been the gold standard for assessing such lesions, but diagnostic difficulties have been described. We aim to estimate the diagnostic accuracy of VS in differentiating early glottic cancer from noninvasive lesions by conducting a systematic review and meta-analysis of published studies.