Publications by authors named "A Greiner Safi"
Background: In this review, the complicated landscape of breast cancer management is explored with a focus on the promising synergies between ribociclib and endocrine therapy. Ribociclib mainly acts as a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor, which disrupts cell cycle progression necessary for tumor growth. This, in combination with endocrine therapy, aims to produce hormone receptor-positive breast cancers, which is a very relevant subtype with challenging therapeutics.
View Article and Find Full Text PDFBackground: Facial implants have emerged as pivotal tools for both reconstructive and aesthetic skull bone augmentation. Contemporary manufacturing techniques, such as computer-aided design and manufacturing (CAD-CAM) systems, have revolutionized facial implants production, providing the advantages of high-level individualization. However, the absence of standardized facial measurements complicates the ability to accurately compare outcomes across various techniques.
View Article and Find Full Text PDFArticle Synopsis
- Cancer is predicted to rise significantly, with 35 million new cases expected by 2050, mainly impacting low- and middle-income countries, particularly in the SAARC region.
- There is a research investment and output gap in SAARC countries compared to high-income nations, leaving a lack of local studies and clinical trials in crucial areas like targeted therapy and immunotherapy.
- Addressing the challenges of healthcare access, cultural and economic barriers, and limited funding in SAARC countries requires collaboration, improved research infrastructure, and local studies to develop practical and affordable cancer treatments.
Article Synopsis
- - The South Asian region faces a critical shortage of oncology professionals due to inadequate education and training programs, impacting the quality of cancer care.
- - Challenges for oncology workers include lack of trained personnel, poor healthcare infrastructure, and limited educational resources.
- - The paper suggests both short-term strategies to enhance training and long-term goals to create self-sufficient cancer care systems through regional collaboration and innovative education.
Article Synopsis
- Cancer care in SAARC countries faces major challenges like poor infrastructure, lack of skilled professionals, and economic issues, leading to delayed diagnoses and worse health outcomes.
- There are significant disparities in healthcare systems across the region, with some countries providing free public services while others rely heavily on out-of-pocket payments, creating financial inequities for cancer patients.
- To improve cancer care, coordinated efforts are needed, including better infrastructure, expanded health insurance, and national cancer control programs, along with regional collaboration to ensure equitable access and advance health goals.