Publications by authors named "A Grech"
Purpose: Dietary macronutrients significantly impact cardiometabolic health, yet research often focuses on individual macronutrient relationships. This study aimed to explore the associations between dietary macronutrient composition and cardiometabolic health.
Methods: This study included 33,681 US adults (49.
Assessing the Trajectory of Bipolar Disorder Effectively in Order to Treat Effectively.
Psychiatr Danub
September 2024
Accurate diagnosis of mood disorders, particularly depression and bipolar disorder, is essential for effective treatment planning and patient management. This article emphasizes the need for systematic symptom assessment and longitudinal analysis in facilitating the precise diagnosis and planning appropriate treatment interventions. By meticulously evaluating the symptomatology and delineating the longitudinal trajectory of the illness, clinicians can distinguish between unipolar depression and bipolar disorder, and therefore optimise patient outcomes.
View Article and Find Full Text PDFAssessing the Trajectory of Schizophrenia Effectively in Order to Treat Effectively.
Psychiatr Danub
September 2024
Article Synopsis
- Schizophrenia is a complex disorder with varied symptom trajectories that significantly affect patient outcomes; studying these trajectories can help assess treatment options and results.
- The Positive and Negative Syndrome Scale (PANSS) can be used repeatedly in clinical settings to measure symptom changes over time, highlighting the importance of longitudinal studies in understanding these trajectories.
- Research shows variability in positive symptom trajectories, with some patients experiencing remission while others have persistent symptoms; negative symptoms generally show limited improvement and are linked to poorer social and cognitive functioning, all of which affect overall treatment effectiveness.
Objective: The COVID-19 pandemic was, and continues to be, uniquely experienced by women in the perinatal period and their families. Whilst long-term impacts of the pandemic are unknown, exposures in pregnancy and early life have impacts across the life-course and future generations. The objective of this manuscript was to explore how the pregnancy, postpartum and parenting experiences of a subset of participants from the 'BABY1000' cohort in Sydney, Australia, were affected by the COVID-19 pandemic, and explore associations between these experiences and state anxiety.
View Article and Find Full Text PDFThe role of dietary macronutrients and energy intake in the aging process has been well-established. However, previous research has mainly focused on the association between leukocyte telomere length (LTL) and individual macronutrients, while the effects of macronutrient composition on LTL remain unclear. This cross-sectional analysis involved 4130 US adults (44.
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