; REACTIONS OF ASTROCYTES AND MICROGLIA OF THE SENSORIMOTOR CORTEX AT LIGATION OF THE CAROTID ARTERY, SENSITIZATION OF THE BRAIN ANTIGEN AND THEIR COMBINATION.

The aim of the work is to identify changes in the state of astrocytes and microglia with unilateral ligation of the carotid artery, sensitization with the cerebral antigen and their combination in the sensorimotor cortex in rats.; Studies were performed on 185 male Wistar white rats weighing 260-290 g. The brain was examined 1, 3, 10, 30 and 90 days after surgery and, respectively, 12 (1), 15 (3), 22 (10 ), 42 (30), 102 (90) days after sensitization (surgical intervention).

[Content of fibroblasts, macrophages, granulocytes and lymphocytes in the connective tissue regenerate of the skin in wound healing as affected by noradrenaline, acetylcholine, propranolol and atropine].

Effects of acetylcholine, noradrenaline, atropine and propranolol on cell number in connective tissue regenerates of the skin in wound healing were studied in white rats. Noradrenaline causes the decrease of inflammatory reaction, fibroblast content in regenerate and basophilia of their cytoplasm. Acetylcholine conversely increases cell reaction, but slows down the re-modelling of connective tissue regenerate.

[Morphologic and histochemical changes of skin nervous apparatus in wound healing following local action of noradrenaline and acetylcholine].

The effect of noradrenaline and acetylcholine on the innervation of skin regenerates in albino rats was studied. It was demonstrated that noradrenaline increased resistive capacity of skin nerve elements to trauma and decelerated the degeneration of impaired elements; promoted skin regenerate neurotization, nerve fibres sprouting and tropism to epidermis; increased monoamine oxidase activity and catecholamine content in adrenergic nerve fibres. Acetylcholine decreases the nerve elements resistive capacity to trauma and accelerates degenerative processes, amplifies peripheral glia reaction; decelerates and activity in appropriate conductors and causes the appearance of basket like plexuses around epidermal invaginating outgrowths.

[Morpho-functional aspects of pathogenesis and surgical treatment of the abdominal wall hernia in elderly and senile patients].

The abdominal wall tissues atrophy was revealed while histological and electromyographic investigation in 16 patients with primary hernia (the mild one) and in 17--with secondary, recurrent and postoperative (much more significant atrophy). The data obtained are applied for the choice of optimal method of operation conduction.

[The vascularization of skin connective-tissue regenerates during wound healing under exposure to neurotransmitters and their antagonists].

Vascularization of skin regenerates was studied in wound healing as affected by noradrenaline (NA), acetylcholine (Ach), propranolole (PR) and atropine (AT). Regenerate vascularization was reduced under NA and AT effect, while Ach and PR promote its increase. Deviation extent of values of granulation tissue vessels specific length (SLV) (by 7th posttraumatic day) increases in proportion with the drug dose.