Publications by authors named "A Goyette"
Co-Constructing a Community-Based Telemedicine Program for People With Opioid Use Disorder During the COVID-19 Pandemic: Lessons Learned and Implications for Future Service Delivery.
JMIR Public Health Surveill
July 2023
The COVID-19 pandemic triggered unprecedented expansion of telemedicine, including in the delivery of opioid agonist treatment (OAT) for people with opioid use disorder (OUD). However, many people with OUD lack the technological resources necessary for remote care, have complex needs, and are underserved, with precarious access to mainstream services. To address the needs of these individuals, we devised a unique program to deliver OAT via telemedicine with the support of community outreach workers in Montreal (Quebec, Canada).
View Article and Find Full Text PDFPhosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a negative regulator of AKT/mTOR signaling pathway. Mutations in PTEN are found in patients with autism, epilepsy, or macrocephaly. In mouse models, Pten loss results in neuronal hypertrophy, hyperexcitability, seizures, and ASD-like behaviors.
View Article and Find Full Text PDFMultidrug-resistant (MDR) Shigella sonnei have become prevalent among men who have sex with men and have become a global public health concern. From June 2017 to April 2019, 32 men were infected with MDR S. sonnei acquired locally, in Montréal, which was suggestive of an outbreak.
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- The ITSN1 gene is crucial for brain development, with recent studies showing that de novo variants in this gene are linked to neurodevelopmental disorders, particularly autism and intellectual disability.
- This study utilized trio exome sequencing on a patient with autism and other cognitive difficulties, along with data from other affected patients globally, to explore the genetic relationships and variants within the ITSN1 gene.
- The findings revealed ten new patients with specific ITSN1 variants, indicating a strong connection to disorders such as autism and intellectual disability, and suggested that different types of mutations in ITSN1 affect its function and are more common in certain regions of the gene.
: Since 2007, all Canadian provinces and territories have had a publicly funded program for vaccination against human papillomavirus (HPV) infection. The objective of this study was to describe the evolution of these vaccination programs. : This was a targeted literature review of public HPV vaccination programs and vaccination coverage rates, based on information provided by jurisdictional public health authorities.
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