Publications by authors named "A Gouskos"
Article Synopsis
- The study investigates how often to screen critically ill adults on ventilators and the best method for conducting spontaneous breathing trials (SBT) to successfully extubate them.
- It involves a randomized clinical trial with 797 participants who required mechanical ventilation, comparing once-daily and more frequent screenings alongside two SBT techniques: pressure-supported and T-piece.
- Results show no significant differences in the time to successful extubation based on screening frequency or SBT technique, indicating that both methods may be similarly effective.
Article Synopsis
- - The study aimed to define what constitutes "patient-important" upper gastrointestinal bleeding during critical illness for a randomized trial, focusing on the perspectives of ICU survivors and their family members.
- - Using interviews and focus groups, researchers gathered qualitative data, which revealed that patient-important bleeding is linked to serious outcomes like death, disability, and extended hospital stays, along with specific medical interventions.
- - Findings highlighted that patients and families view gastrointestinal bleeding differently than traditional clinical definitions, emphasizing the context and effects of treatments as crucial to understanding its importance.
Article Synopsis
- The FAST-NAWC trial is a multicenter study that aims to compare different screening frequencies and techniques for spontaneous breathing trials in critically ill patients on ventilation in 20 North American ICUs.
- The original protocols have been updated to include COVID-19 patients, and changes were made to the statistical analysis plan to accommodate data reporting for both COVID-19 and non-COVID-19 participants.
- The trial has been registered on Clinical Trials.gov, and this update outlines the key protocol modifications and their purpose before the final follow-up and data analysis phases.
Article Synopsis
- - The study aims to understand the values and preferences of patients and families regarding upper gastrointestinal bleeding treatments, challenging traditional definitions that are primarily clinical.
- - Utilizing a mixed-methods approach, the research involves interviews and focus groups with ICU survivors and their families after providing educational materials to gather their insights.
- - Approved by ethics boards, the findings will contribute to creating meaningful trial outcomes for stress ulcer prophylaxis and be published for wider dissemination.
Neuromuscular blockade in patients with ARDS: a rapid practice guideline.
Intensive Care Med
November 2020
The aim of this Intensive Care Medicine Rapid Practice Guideline (ICM-RPG) is to formulate an evidence-based guidance for the use of neuromuscular blocking agents (NMBA) in adults with acute respiratory distress syndrome (ARDS). The panel comprised 20 international clinical experts from 12 countries, and 2 patient representatives. We adhered to the methodology for trustworthy clinical practice guidelines and followed a strict conflict of interest policy.
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